A REVIEW OF CONOLIDINE ALKALOID FOR CHRONIC PAIN

A Review Of Conolidine alkaloid for chronic pain

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Most recently, it has been identified that conolidine and the above derivatives act around the atypical chemokine receptor three (ACKR3. Expressed in similar regions as classical opioid receptors, it binds to a wide array of endogenous opioids. Compared with most opioid receptors, this receptor acts like a scavenger and does not activate a next mes

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